{"id":9186,"date":"2026-05-05T13:36:52","date_gmt":"2026-05-05T13:36:52","guid":{"rendered":"https:\/\/fakt24.biz.ua\/?p=9186"},"modified":"2026-05-05T13:36:52","modified_gmt":"2026-05-05T13:36:52","slug":"pokud-se-vam-v-uchu-objevi-tento-priznak-je-to-varovny-signal-ze-mate","status":"publish","type":"post","link":"https:\/\/fakt24.biz.ua\/?p=9186","title":{"rendered":"Pokud se v\u00e1m v uchu objev\u00ed tento p\u0159\u00edznak, je to varovn\u00fd sign\u00e1l, \u017ee m\u00e1te\u2026"},"content":{"rendered":"\n
    \n
  1. Co je Frank\u016fv p\u0159\u00edznak?
    Frank\u016fv p\u0159\u00edznak ozna\u010duje diagon\u00e1ln\u00ed r\u00fdhu prob\u00edhaj\u00edc\u00ed p\u0159ibli\u017en\u011b v \u00fahlu 45\u00b0 p\u0159es u\u0161n\u00ed lal\u016f\u010dek, zn\u00e1mou tak\u00e9 jako diagon\u00e1ln\u00ed r\u00fdha u\u0161n\u00edho lal\u016f\u010dku (DELC). Poprv\u00e9 ji popsal Dr. Sanders T. Frank, kter\u00fd si tuto r\u00fdhu v\u0161iml u 20 pacient\u016f s anginou pectoris.<\/li>\n<\/ol>\n\n\n\n

    Zpo\u010d\u00e1tku byl spojov\u00e1n s ischemickou chorobou srde\u010dn\u00ed, ale pozd\u011bj\u0161\u00ed v\u00fdzkum zjistil, \u017ee stejn\u00fd z\u00e1hyb se vyskytuje i u pacient\u016f s onemocn\u011bn\u00edm perifern\u00edch c\u00e9v a cerebrovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm. V podstat\u011b m\u016f\u017ee b\u00fdt z\u00e1hyb v oblasti u\u0161n\u00edho lal\u016f\u010dku sp\u00ed\u0161e vn\u011bj\u0161\u00edm znakem \u0161patn\u00e9ho krevn\u00edho ob\u011bhu, a to i v koron\u00e1rn\u00edch tepn\u00e1ch, ne\u017e jen zn\u00e1mkou st\u00e1rnut\u00ed.<\/p>\n\n\n\n

      \n
    1. Kdo nej\u010dast\u011bji vykazuje Frankovo \u200b\u200bznamen\u00ed?<\/li>\n<\/ol>\n\n\n\n

      \u010casto se vyskytuje u pacient\u016f na kardiologick\u00fdch klinik, zejm\u00e9na u t\u011bch, kte\u0159\u00ed podstoupili bypass koron\u00e1rn\u00ed tepny. P\u0159\u00edtomnost tohoto z\u00e1hybu v\u0161ak u jinak zdrav\u00fdch jedinc\u016f tak\u00e9 nazna\u010duje zv\u00fd\u0161en\u00e9 riziko c\u00e9vn\u00edch onemocn\u011bn\u00ed. Je zaj\u00edmav\u00e9, \u017ee tento p\u0159\u00edznak nekoreluje s t\u011blesnou hmotnost\u00ed, proto\u017ee se m\u016f\u017ee objevit jak u \u0161t\u00edhl\u00fdch, tak u lid\u00ed s nadv\u00e1hou.<\/p>\n\n\n\n

        \n
      1. Mo\u017en\u00e9 mechanismy Frankova p\u0159\u00edznaku
        P\u0159esn\u00e1 p\u0159\u00ed\u010dina z\u016fst\u00e1v\u00e1 nejist\u00e1. N\u011bkter\u00e9 studie zjistily, \u017ee za n\u011bj m\u016f\u017ee b\u00fdt zodpov\u011bdn\u00e9 mikrovaskul\u00e1rn\u00ed onemocn\u011bn\u00ed ve st\u0159edn\u00edm laloku ucha \u2013 oblasti z\u00e1sobovan\u00e9 termin\u00e1ln\u00edmi tepnami. Jin\u00e9 zaznamenaly souvislost mezi zkr\u00e1cen\u00fdmi telomerami u japonsk\u00fdch pacient\u016f s metabolick\u00fdm syndromem a obecn\u00fdmi procesy st\u00e1rnut\u00ed c\u00e9v a ateroskler\u00f3zy.<\/li>\n\n\n\n
      2. Stupn\u011b z\u00e1va\u017enosti<\/li>\n<\/ol>\n\n\n\n

        Vzhled Frankova znaku lze kategorizovat podle jeho hloubky, d\u00e9lky, symetrie a \u00fahlu, co\u017e m\u016f\u017ee pomoci odhadnout kardiovaskul\u00e1rn\u00ed riziko:<\/p>\n\n\n\n

        Ne\u00fapln\u00fd z\u00e1hyb na jednom u\u0161n\u00edm lal\u016f\u010dku \u2013 nejm\u00e9n\u011b z\u00e1va\u017en\u00fd
        \u00dapln\u00fd z\u00e1hyb na jednom u\u0161n\u00edm lal\u016f\u010dku
        Z\u00e1hyby na obou u\u0161n\u00edch lal\u016f\u010dc\u00edch \u2013 nejz\u00e1va\u017en\u011bj\u0161\u00ed
        Z\u00e1v\u011br<\/p>\n\n\n\n

        Frank\u016fv p\u0159\u00edznak s\u00e1m o sob\u011b nepotvrzuje p\u0159\u00edtomnost srde\u010dn\u00edho onemocn\u011bn\u00ed, slou\u017e\u00ed jako v\u010dasn\u00fd varovn\u00fd sign\u00e1l. D\u00edky tomu je cenn\u00fd pro screening a vyvol\u00e1n\u00ed podez\u0159en\u00ed na ischemickou chorobu srde\u010dn\u00ed, zejm\u00e9na u osob mlad\u0161\u00edch 60 let. Pokud tento p\u0159\u00edznak pozorujete u sebe, p\u0159\u00edtele nebo \u010dlena rodiny, je moudr\u00e9 doporu\u010dit kardiovaskul\u00e1rn\u00ed vy\u0161et\u0159en\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"Zpo\u010d\u00e1tku byl spojov\u00e1n s ischemickou chorobou srde\u010dn\u00ed, ale pozd\u011bj\u0161\u00ed v\u00fdzkum zjistil, \u017ee stejn\u00fd z\u00e1hyb se vyskytuje i u pacient\u016f s onemocn\u011bn\u00edm perifern\u00edch c\u00e9v \n [...]<\/a>","protected":false},"author":1,"featured_media":9187,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9186","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/9186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9186"}],"version-history":[{"count":1,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/9186\/revisions"}],"predecessor-version":[{"id":9188,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/9186\/revisions\/9188"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/media\/9187"}],"wp:attachment":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9186"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9186"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}