Rakovina prsu a rakovina vaje\u010dn\u00edk\u016f pat\u0159\u00ed mezi nej\u010dast\u011bji diagnostikovan\u00e9 druhy rakoviny u \u017een na cel\u00e9m sv\u011bt\u011b.<\/p>\n\n\n\n
A\u010dkoli se jedn\u00e1 o r\u016fzn\u00e9 org\u00e1ny, st\u00e1le v\u00edce v\u00fdzkum\u016f nazna\u010duje, \u017ee by mohly b\u00fdt biologicky p\u0159\u00edbuzn\u00e9, zejm\u00e9na na genetick\u00e9 \u00farovni.<\/p>\n\n\n\n
Pochopen\u00ed tohoto vztahu pom\u00e1h\u00e1 \u017een\u00e1m \u010dinit informovan\u011bj\u0161\u00ed rozhodnut\u00ed o prevenci, n\u00e1sledn\u00e9 p\u00e9\u010di a l\u00e9\u010db\u011b.<\/p>\n\n\n\n
Jedn\u00edm z kl\u00ed\u010dov\u00fdch prvk\u016f spojuj\u00edc\u00edch rakovinu prsu a rakovinu vaje\u010dn\u00edk\u016f jsou mutace gen\u016f BRCA1 a BRCA2.<\/p>\n\n\n\n
Tyto geny jsou zodpov\u011bdn\u00e9 za opravu po\u0161kozen\u00e9 DNA a ochranu t\u011bla p\u0159ed rozvojem rakoviny.<\/p>\n\n\n\n
Kdy\u017e dojde k mutaci BRCA1 nebo BRCA2, ochrann\u00e9 mechanismy selh\u00e1vaj\u00ed a riziko onemocn\u011bn\u00ed se v\u00fdrazn\u011b zvy\u0161uje.<\/p>\n\n\n\n
\u017deny s mutac\u00ed BRCA1 mohou m\u00edt celo\u017eivotn\u00ed riziko vzniku rakoviny prsu a\u017e 72 procent.<\/p>\n\n\n\n
U rakoviny vaje\u010dn\u00edk\u016f maj\u00ed nositel\u00e9 t\u00e9to mutace riziko a\u017e 44 procent.<\/p>\n\n\n\n
Mutace BRCA2 tak\u00e9 zvy\u0161uje riziko, i kdy\u017e v o n\u011bco men\u0161\u00ed m\u00ed\u0159e.<\/p>\n\n\n\n
U \u017een s mutac\u00ed BRCA2 se odhaduje a\u017e 69% riziko rakoviny prsu a p\u0159ibli\u017en\u011b 17% riziko rakoviny vaje\u010dn\u00edk\u016f.<\/p>\n\n\n\n
Tyto mutace mohou b\u00fdt zd\u011bd\u011bny jak od matky, tak od otce.<\/p>\n\n\n\n
To znamen\u00e1, \u017ee i jedin\u00fd p\u0159\u00edpad rakoviny prsu nebo vaje\u010dn\u00edk\u016f v rodin\u011b m\u016f\u017ee m\u00edt genetick\u00fd v\u00fdznam.<\/p>\n\n\n\n
Rodinn\u00e1 anamn\u00e9za proto hraje p\u0159i hodnocen\u00ed rizika velmi d\u016fle\u017eitou roli.<\/p>\n\n\n\n
Pokud va\u0161e matka, sestra, babi\u010dka nebo teta m\u011bla rakovinu prsu nebo vaje\u010dn\u00edk\u016f, m\u016f\u017ee b\u00fdt va\u0161e riziko vy\u0161\u0161\u00ed.<\/p>\n\n\n\n
To plat\u00ed zejm\u00e9na v p\u0159\u00edpad\u011b, \u017ee se rakovina objev\u00ed v mlad\u00e9m v\u011bku.<\/p>\n\n\n\n
N\u011bkdy se v rodin\u011b vyskytuje pouze jeden typ rakoviny, p\u0159esto m\u016f\u017ee b\u00fdt p\u0159\u00ed\u010dina spole\u010dn\u00e1.<\/p>\n\n\n\n
V takov\u00fdch p\u0159\u00edpadech se vyplat\u00ed zv\u00e1\u017eit genetickou konzultaci.<\/p>\n\n\n\n
Testov\u00e1n\u00ed na mutace BRCA umo\u017e\u0148uje lep\u0161\u00ed posouzen\u00ed individu\u00e1ln\u00edho rizika onemocn\u011bn\u00ed.<\/p>\n\n\n\n
Znalost va\u0161eho genetick\u00e9ho statusu v\u00e1m umo\u017e\u0148uje napl\u00e1novat vhodnou prevenci.<\/p>\n\n\n\n
Krom\u011b genetick\u00fdch faktor\u016f existuj\u00ed i \u200b\u200bdal\u0161\u00ed prvky spole\u010dn\u00e9 pro oba druhy rakoviny.<\/p>\n\n\n\n
Riziko vzniku onemocn\u011bn\u00ed se zvy\u0161uje s v\u011bkem, zejm\u00e9na po pades\u00e1tce.<\/p>\n\n\n\n
Dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed hormon\u00e1ln\u00ed substitu\u010dn\u00ed terapie po menopauze m\u016f\u017ee tak\u00e9 zv\u00fd\u0161it riziko.<\/p>\n\n\n\n
D\u016fle\u017eit\u00e1 je tak\u00e9 reproduk\u010dn\u00ed historie \u017eeny.<\/p>\n\n\n\n
\u010casn\u00fd n\u00e1stup menstruace nebo pozdn\u00ed menopauza jsou spojeny s m\u00edrn\u011b vy\u0161\u0161\u00edm rizikem.<\/p>\n\n\n\n
Ne\u00fasp\u011bch v ot\u011bhotn\u011bn\u00ed nebo narozen\u00ed prvn\u00edho d\u00edt\u011bte v pozd\u011bj\u0161\u00edm v\u011bku je \u010dast\u011bji spojov\u00e1no s rakovinou vaje\u010dn\u00edk\u016f.<\/p>\n\n\n\n
Pov\u011bdom\u00ed o souvislosti mezi t\u011bmito druhy rakoviny otev\u00edr\u00e1 cestu k \u00fa\u010dinn\u011bj\u0161\u00edm preventivn\u00edm opat\u0159en\u00edm.<\/p>\n\n\n\n
\u017deny s vy\u0161\u0161\u00edm rizikem mohou pot\u0159ebovat d\u0159\u00edv\u011bj\u0161\u00ed a \u010dast\u011bj\u0161\u00ed screeningov\u00e9 testy.<\/p>\n\n\n\n
Pat\u0159\u00ed sem mamografie, magnetick\u00e1 rezonance prsu a vy\u0161et\u0159en\u00ed vaje\u010dn\u00edk\u016f.<\/p>\n\n\n\n
V n\u011bkter\u00fdch p\u0159\u00edpadech l\u00e9ka\u0159i doporu\u010duj\u00ed pravideln\u00e9 ultrazvukov\u00e9 vy\u0161et\u0159en\u00ed p\u00e1nve nebo krevn\u00ed testy.<\/p>\n\n\n\n
N\u011bkter\u00e9 \u017eeny se tak\u00e9 rozhodnou podstoupit preventivn\u00ed l\u00e9\u010dbu, aby sn\u00ed\u017eily riziko onemocn\u011bn\u00ed.<\/p>\n\n\n\n
To m\u016f\u017ee zahrnovat odstran\u011bn\u00ed prsou, vaje\u010dn\u00edk\u016f nebo vejcovod\u016f p\u0159edt\u00edm, ne\u017e se onemocn\u011bn\u00ed rozvine.<\/p>\n\n\n\n
Dal\u0161\u00ed mo\u017enost\u00ed je u\u017e\u00edv\u00e1n\u00ed l\u00e9k\u016f, kter\u00e9 sni\u017euj\u00ed riziko rakoviny prsu, jako je tamoxifen.<\/p>\n\n\n\n
Mnoho \u017een si neuv\u011bdomuje, \u017ee rozvoj jednoho z t\u011bchto druh\u016f rakoviny zvy\u0161uje riziko vzniku druh\u00e9ho.<\/p>\n\n\n\n
Proto je po diagn\u00f3ze rakoviny prsu vhodn\u00e9 prodiskutovat s l\u00e9ka\u0159em sledov\u00e1n\u00ed vaje\u010dn\u00edk\u016f.<\/p>\n\n\n\n
Podobn\u011b je t\u0159eba v p\u0159\u00edpad\u011b rakoviny vaje\u010dn\u00edk\u016f v\u011bnovat pozornost vy\u0161et\u0159en\u00ed prs\u016f.<\/p>\n\n\n\n
V\u010dasn\u00e1 detekce je kl\u00ed\u010dov\u00e1 pro progn\u00f3zu a \u00fa\u010dinnost l\u00e9\u010dby.<\/p>\n\n\n\n
Rakovina prsu je \u010dasto odhalena d\u0159\u00edve pomoc\u00ed screeningov\u00fdch test\u016f.<\/p>\n\n\n\n
Rakovina vaje\u010dn\u00edk\u016f je n\u011bkdy diagnostikov\u00e1na pozd\u011b, proto\u017ee jej\u00ed p\u0159\u00edznaky jsou nespecifick\u00e9.<\/p>\n\n\n\n
Proto je tak d\u016fle\u017eit\u00e9 zn\u00e1t sv\u00e1 vlastn\u00ed rizika a rodinnou anamn\u00e9zu.<\/p>\n\n\n\n
Souvislost mezi rakovinou prsu a rakovinou vaje\u010dn\u00edk\u016f je skute\u010dn\u00e1 a potvrzen\u00e1 v\u00fdzkumem.<\/p>\n\n\n\n
To je obzvl\u00e1\u0161t\u011b d\u016fle\u017eit\u00e9 pro \u017eeny s mutacemi BRCA nebo pozitivn\u00ed rodinnou anamn\u00e9zou.<\/p>\n\n\n\n
Pokud m\u00e1te jak\u00e9koli obavy ohledn\u011b sv\u00e9ho rizika, stoj\u00ed za to si o tom promluvit se sv\u00fdm l\u00e9ka\u0159em.<\/p>\n\n\n\n
Genetick\u00e9 testov\u00e1n\u00ed a informovan\u00e1 prevence mohou nejen poskytnout klid, ale tak\u00e9 zachr\u00e1nit \u017eivoty.<\/p>\n","protected":false},"excerpt":{"rendered":"Rakovina prsu a rakovina vaje\u010dn\u00edk\u016f pat\u0159\u00ed mezi nej\u010dast\u011bji diagnostikovan\u00e9 druhy rakoviny u \u017een na cel\u00e9m sv\u011bt\u011b. A\u010dkoli se jedn\u00e1 o r\u016fzn\u00e9 org\u00e1ny, st\u00e1le \n [...]<\/a>","protected":false},"author":1,"featured_media":4721,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4720","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/4720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4720"}],"version-history":[{"count":1,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/4720\/revisions"}],"predecessor-version":[{"id":4722,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/posts\/4720\/revisions\/4722"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=\/wp\/v2\/media\/4721"}],"wp:attachment":[{"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fakt24.biz.ua\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}